EDITORIAL-DETAILS (JPDM)
Santhi Gorantla
Assistant Professor
University of Nebraska Medical Center
USA
Biography
Dr. Santhi Gorantla is an Assistant Professor in the Department of Pharmacology and Experiment Neuroscience at University of Nebraska Medical Center (UNMC), Omaha, NE. She has been a faculty member since 2007. Dr. Gorantla got her M.Sc. in Biochemistry and pursued Ph.D. in Immunology at University of Hyderabad, India. She got her first postdoctoral training in Gene therapy strategies for HIV in humanized mouse models at Colorado State University, and her second postdoctoral training was on the HIV-1 induced neuropathogenesis in humanized mouse models and immune modulatory therapeutic approaches. Dr. Gorantla’s research focuses on HIV-1 pathobiology, therapeutic approaches to target brain HIV-1 reservoirs, immunomodulatory approaches to reduce inflammation. Using a novel humanized mouse model of chronic HIV-1 infection, Dr. Gorantla studies immunopathology, neuropathology and therapeutics. Humanized mice with human immune system are developed by transplanting human CD34+ stem cells from umbilical cord blood at birth. She has published more than 30 peer reviewed journal articles and contributed to five book chapters. Dr. Gorantla is actively involved in teaching Pharmacology courses and drugs abuse on Immune system to graduate students. Currently her work is funded by National Institute of Health and Nebraska Stem Cell grants.
Research Interest
HIV-1, inflammation, neuropathology, humanized mice, nanoparticles, cannabinoids, anti-retrovirals, induce pluripotent cells, stem cells.