Editorial-Details (JAAA)
Zhuoying Feng
Cleveland Clinic Lerner Research Institute
USA
Biography
Dr. Zhuoying Feng is a biomedical scientist with interdisciplinary research expertise spanning virology, cancer biology, immunology, metabolism, and microbiome-related research. She currently serves as a Postdoctoral Fellow at the Cleveland Clinic Lerner Research Institute, where her research focuses on the alcohol–gut–brain axis and the role of butyrate in neuroinflammation. Previously, she conducted postdoctoral research in infection and cancer biology at the Cleveland Clinic, investigating viral protein–host interactions, antiviral mechanisms, and protein function using advanced genetic and molecular approaches. Dr. Feng received her Ph.D. in Biomedical Science from City University of Hong Kong, where she investigated viral infections, N6-methyladenosine (m6A) RNA modification, cytokine responses, and cholesterol metabolism in relation to viral replication. Her doctoral research contributed to a better understanding of HSV-1 infection, Enterovirus A71-associated immune responses, and hepatitis B virus replication. She also holds a Master's degree in Human Anatomy from Binzhou Medical University and a medical degree combining Traditional Chinese Medicine and Western Medicine from Southern Medical University. Her research experience includes viral engineering, reverse genetics, pseudotyped rVSV systems, tetracycline-inducible ORF library screening, protein purification, TALEN-mediated genome integration, monoclonal cell selection, organoid culture, and molecular and cellular approaches to cancer and infectious disease research. She has authored and co-authored publications in journals including Hepatology Communications, Genes & Diseases, Theranostics, Cytokine, and Oncotarget. Her work reflects a strong interest in understanding molecular mechanisms underlying infectious diseases, cancer progression, inflammation, and metabolic disorders.
Research Interest
Virology and viral pathogenesis, Host–virus interactions and antiviral mechanisms, Viral protein–host receptor/ligand interactions, Viral RNA modifications including m6A methylation, Cancer biology and tumor progression, Cancer stem cells and cellular metabolism, Lipid and cholesterol metabolism, Immunology and inflammatory signaling, Cytokine and chemokine responses to viral infections, Metabolic dysfunction-associated steatotic liver disease (MASLD), Gut microbiome and the gut–brain axis, Butyrate and microbial metabolites, Neuroinflammation, Organoid-based disease modeling, Molecular mechanisms of infectious and metabolic diseases, Genetic engineering, reverse genetics, and functional genomics

