EDITORIAL-DETAILS (JSCR)
Jean-Marc Lemaitre
University Montpellier
France
Biography
Among major achievements, he discovered the missing DNA replication initiating factor responsible for the acquisition of the competence to replicate for embryonic development, postulated 30 yearsago by J.Gurdon (Lemaitre et al., Nature 2002). He set up a new concept in the DNA replication field, showing that the replication origin selection program for development, could be reprogrammed through a mitotic remodeling of the chromosome structure in mimicking nuclear transfer experiments (Lemaitre et al.,Cell 2005, Cuvier et al., 2008, Lemaitre and Méchali patent 2008).
Research Interest
understanding of the molecular mechanisms regulating physiological and pathological proliferation disorders, and development, replication senescence and reprogramming.